:root{font-family:-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,sans-serif;line-height:1.5;font-weight:400;font-synthesis:none;text-rendering:optimizeLegibility;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale}*{box-sizing:border-box}:root{--bg-color: #f8f9fa;--card-bg: #ffffff;--text-primary: #222222;--text-secondary: #666666;--border-color: #dddddd;--input-bg: #ffffff;--accent-color: #007bff;--accent-hover: #0056b3;--dropzone-hover: #f0f7ff;--danger-color: #dc3545}@media(prefers-color-scheme:dark){:root{--bg-color: #121212;--card-bg: #1e1e1e;--text-primary: #e0e0e0;--text-secondary: #aaaaaa;--border-color: #333333;--input-bg: #2d2d2d;--accent-color: #3793ff;--accent-hover: #5aa4ff;--dropzone-hover: #1a2635}}body{background-color:var(--bg-color);color:var(--text-primary);margin:0;padding:10px;font-family:-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,sans-serif;transition:background-color .3s ease}.app-container{max-width:1500px;margin:40px auto;padding:0 20px}header h1{color:var(--text-primary)}.tab-nav{display:flex;gap:20px;border-bottom:2px solid var(--border-color);margin-bottom:25px}.tab-btn{padding:12px 20px;cursor:pointer;border:none;background:none;font-weight:700;color:var(--text-secondary);border-bottom:3px solid transparent;transition:all .2s ease}.tab-btn.active{color:var(--accent-color);border-bottom-color:var(--accent-color)}.dropzone{border:2px dashed var(--text-secondary);padding:30px;border-radius:8px;text-align:center;background:var(--card-bg);color:var(--text-secondary);cursor:pointer;transition:background .2s ease}.dropzone.is-active{background:var(--dropzone-hover);border-color:var(--accent-color)}.file-card,.table-container{background:var(--card-bg);border:1px solid var(--border-color);border-radius:8px;padding:20px;margin-bottom:15px;box-shadow:0 2px 4px #0003}.input-group label{font-size:11px;font-weight:700;color:var(--text-secondary);margin-bottom:5px}input[type=number],.unit-dropdown{background-color:var(--input-bg);color:var(--text-primary);border:1px solid var(--border-color);padding:8px;border-radius:4px}.app-container input[type=text],.app-container input[type=number],.app-container select,.app-container textarea{background-color:var(--input-bg)!important;color:var(--text-primary)!important;border:1px solid var(--border-color)!important}.app-container input::placeholder,.app-container textarea::placeholder{color:var(--text-secondary);opacity:1}input:focus,select:focus{outline:2px solid var(--accent-color);outline-offset:-1px}.config-table{width:100%;border-collapse:collapse;color:var(--text-primary)}.config-table th{border-bottom:2px solid var(--border-color);text-align:left;padding:12px;font-size:12px;color:var(--text-secondary)}.config-table td{padding:12px;border-bottom:1px solid var(--border-color)}.row-highlight{background-color:var(--dropzone-hover)}.row-highlight-substrate{background-color:#ff7f001f}.row-highlight-protein{background-color:#4daf4a1f}.submit-btn{background-color:var(--accent-color);color:#fff;padding:12px 24px;border:none;border-radius:4px;cursor:pointer;font-weight:700;width:100%;min-height:44px;display:inline-flex;align-items:center;justify-content:center;transition:background .2s}.submit-btn:hover:not(:disabled){background-color:var(--accent-hover)}.submit-btn:disabled{filter:grayscale(1);opacity:.5;cursor:not-allowed}.btn-spinner{width:18px;height:18px;border:2px solid rgba(255,255,255,.35);border-top-color:#fff;border-radius:50%;animation:btn-spin .8s linear infinite}@keyframes btn-spin{to{transform:rotate(360deg)}}.remove-btn-small{color:var(--danger-color);background:none;border:1px solid var(--danger-color);padding:4px 8px;border-radius:4px;cursor:pointer}.remove-btn-small:hover{background:var(--danger-color);color:#fff}.parse-failures{margin:16px 0;padding:14px 16px;border:1px solid var(--danger-color);border-radius:6px;background:#dc354514}.parse-failures h4{margin:0 0 10px;color:var(--danger-color);font-size:.95rem}.parse-failures ul{list-style:none;margin:0;padding:0}.parse-failures li{display:flex;flex-direction:column;gap:3px;padding:8px 0;border-top:1px solid rgba(220,53,69,.2)}.parse-failures li:first-child{border-top:0}.parse-failures span{color:var(--text-secondary);font-size:.85rem}.no-spinner::-webkit-inner-spin-button,.no-spinner::-webkit-outer-spin-button{-webkit-appearance:none;margin:0}.input-with-unit{display:flex;gap:8px}.analysis-summary-grid{display:grid;grid-template-columns:1fr 1fr;gap:20px;margin-bottom:20px;border:1px solid var(--border-color, #eee)}.summary-column h4{margin-top:0;border-bottom:1px solid #666;padding-bottom:5px}.graphs-container img{background:#fff;padding:10px;border-radius:8px;box-shadow:0 4px 12px #0000001a}